Research

Research from the Regeneron Genetics Center available for the global scientific community.

Genetic associations with body mass index (BMI)

This page hosts summary statistics for the genetic associations with body mass index (BMI) generated in the Mexico City Prospective Study (MCPS) or in the Myode Community Health Initiative Geisinger Health System (GHS) cohort.

Genetic associations with BMI are described in the accompanying publication:

Parsa Akbari, Ankit Gilani, Olukayode Sosina, Jack A. Kosmicki, Lori Khrimian, Yi-Ya Fang, Trikaldarshi Persaud, Victor Garcia, Dylan Sun, Alexander Li, Joelle Mbatchou, Adam Locke, Christian Benner, Niek Verweij, Nan Lin, Sakib Hossain, Kevin Agostinucci, Jonathan V. Pascale, Ercument Dirice, Michael Dunn, Regeneron Genetics Center, DiscovEHR Collaboration, William E. Kraus, Svati H. Shah, Yii-Der I. Chen, Jerome I. Rotter, Daniel J. Rader, Olle Melander, Christopher D. Still, Tooraj Mirshahi, David J. Carey, Jaime Berumen-Campos, Pablo Kuri-Morales, Jesus Alegre-Díaz, Jason M. Torres, Jonathan R. Emberson, Rory Collins, Suganthi Balasubramanian, Alicia Hawes, Marcus Jones, Brian Zambrowicz, Andrew J. Murphy, Charles Paulding, Giovanni Coppola, John D. Overton, Jeffrey G. Reid, Alan Shuldiner, Michael Cantor, Hyun M. Kang, Goncalo R. Abecasis, Katia Karalis, Aris N. Economides, Jonathan Marchini, George D. Yancopoulos, Mark W. Sleeman, Judith Altarejos, Giusy Della Gatta, Roberto Tapia-Conyer, Michal L. Schwartzman, Aris Baras, Manuel A. R. Ferreira, Luca A. Lotta. Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity. Science 373, eabf8683 (2021). DOI: 10.1126/science.abf8683.

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